Table 4 Scales scores evolutions between baseline to acute endpoint (Week 6) and overall endpoint (Week 24)
Manic n = 36 | Hypomanic n = 31 | Mixed n = 26 | Depressive n = 47 | |||||
|---|---|---|---|---|---|---|---|---|
Scale; mean, total score (SD) / 95%CI | Change baseline-acute endpoint | Change baseline-endpoint | Change baseline-acute endpoint | Change baseline-endpoint | Change baseline-acute endpoint | Change baseline-endpoint | Change baseline-acute endpoint | Change baseline-endpoint |
MAThyS without item 5 | −24.8 (29,2) [−35.7; -13.9] | −25.6 (25.6) [−34.5; -16.7] | −33.0 (31.7) [−44.6; -21.3] | −34.4 (34.0) [−46.8; -21.9] | −12.9 (27,0) [−24.2; -1.5] | −26.3 (42.0) [−43.6; -9.0] | 18.0 (26,9) [9.8; 26.1] | 18.2 (33.3) [8.4; 28.0] |
Factor 1 | −21.7 (32.5) [−33.6;-9.8] | −24.5 (28.8) [−34.4;-14.6] | −35.6 (36.6) [−49.0;-22.2] | −34.4 (42.7) [−50.1;-18.7] | −6.1 (32.8) [−19.9;7.8] | −21.8 (44.7) [−40.2; -3.3] | 25.3 (29.1) [16.4;34.1] | 26.9 (34.2) [16.8;36.9] |
Factor 2 | −27.2 (34.6) [−40.1;-14.3] | −26.2 (30.0) [−36.6;-15.7] | −28.4 (33.8) [−40.8;-16.0] | −34.3 (30.1) [−45.3;-23.3] | −24.5 (29.9) [−37.2;-11.9] | −35.7 (45.8) [−54.6;-16.8] | 4.9 (32.0) [−4.7;14.6] | 3.3 (38.3) [−8.0;14.6] |
HAMA | −2.7 (4.9) [−4.5; -0.9] | −2.3 (4.8)[ −3.9; -0.6] | −5.5 (5.9) [−7.7; -3.3] | −5.7 (7.4) [−8.3; -3.0] | −7.3 (6.3) [−9.9; -4.7] | −7.6 (7.9) [−10.8; -4.4] | −6.8 (6.6) [−8.7; -4.8] | −6.8 (7.2) [−8.9; -4.7] |
HAMD-17 | −1.8 (4.6) [−3.5; -0.1] | −1.7 (5.0) [−3.5; 0.0] | −3.1 (4.6) [−4.9; -1.4] | −3.2 (6.4) [−5.6; -0.8] | −5.6 (6.6) [−8.3; -2.9] | −5.5 (6.7) [−8.2; -2.8] | −8.5 (6.2) [−10.4; -6.6] | −8.0 (7.2) [−10.1; -5.9] |
YMRS | −13.7 (9.4) [−17.1; -10.2] | −14.0 (10.9) [−17.8; -10.2] | −13.1 (6.0) [−15.3; -10.9] | −14.5 (7.4) [−17.2; -11.8] | −9. 7 (7.9) [−13.0; -6.3] | −10.6 (8.0) [−13.9; -7.3] | −0.9 (3.5) [−2.0; 0.2] | −0.8 (3.2) [−1.8; 0.2] |