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Table 1 Baseline characteristics of patients included in MATHYS clinical trial in acute mood episode

From: Inhibition/activation in bipolar disorder: validation of the Multidimensional Assessment of Thymic States scale (MAThyS)

  Manic n = 36 Hypomanic n = 31 Mixed n = 26 Depressive n = 48 Global N = 141
Sociodemographic characteristics      
Sex, female (n,%) 19 (52.8) 21 (67.7) 15 (57.7) 25 (52.1) 80 (56.7)
Age (mean, SD) 46.4 (15.3) 45.8 (11.7) 46.6 (12.9) 44.4 (12.0) 45.6 (12.9)
BMI (mean, SD) 24.8 (4.5) 24.7 (5.0) 26.9 (7.8) 24.5 (3.7) 25.1 (5.2)
Status, inpatient (n,%) 26 (72.2) 12 (38.7) 10 (38.5) 24 (50.0) 72 (51.1)
Psychiatric history      
Bipolar type (n,%)      
 I 36 (100.0) 14 (45.2) 26 (100.0) 31 (64.6) 107 (75.9)
 II 0 (0.0) 17 (54.8) 2 (7.7) 17 (35.4) 36 (25.5)
Age at onset (mean, SD) 30.6 (13.9) 34.0 (13.8) 27.4 (10.8) 29.2 (10.4) 30.3 (12.3)
Duration of illness in years (mean, SD) 16.9 (13.9) 12.5 (9.5) 19.3 (14.5) 15.7 (11.6) 15.9 (12.5)
Number of episodes lifetime (mean, SD) 7.5 (4.8) 8.3 (7.6) 6.5 (5.9) 7.2 (5.8) 7.4 (6.0)
Duration of current episode in months (mean, SD) 1.0 (1.5) 2.0 (3.2) 1.7 (1.6) 1.5 (1.5) 1.5 (2.0)
Lifetime substance-use disorder (n,%)      
 Alcohol dependence 2 (5.6) 1 (3.2) 4 (15.4) 3 (6.3) 10 (7.1)
 Alcohol abuse 5 (13.9) 4 (12.9) 6 (23.1) 12 (25.0) 27 (19.1)
 Other substances 1 (2.8) 1 (3.2) 0 (0.0) 4 (8.3) 6 (4.3)
Lifetime suicide attempts (n,%) 10 (29.4) 5 (17.9) 10 (40.0) 18 (39.1) 43 (32.4)
Previous olanzapine treatment (n,%) 16 (44.4) 10 (32.3) 7 (26.9) 17 (35.4) 50 (35.5)
Rating scales      
MAThyS total score (mean, SD) 142.2 (23.0) 137.7 (23.4) 116.2 (21.4) 75.3 (23.9) 113.20 (37.1)
HAMD-17 total score (mean, SD) 6.5 (4.9) 8.4 (5.3) 12.7 (4.8) 16.1 (7.2) 11.4 (7.0)-
YMRS total score (mean, SD) 24.5 (10.3) 17.8 (4.9) 13.0 (7.7) 2. 8 (3.6) 13.7 (11.0)-
HAMA total score (mean, SD) 7.8 (6.3) 11.9 (7.7) 15.5 (7.2) 15.1 (7.4) 12.6 (7.7)
  1. Abbreviations: BMI, Body Mass Index; HAMA, Hamilton Anxiety Scale; HAMD-17, 17-item Hamilton Depression Scale; MAThyS, Multidimensional Assessment of Thymic State; SD, Standard Deviation; YMRS, Young Mania Rating Scale.