Medial temporal lobe function during emotional memory in early Alzheimer’s disease, mild cognitive impairment and healthy ageing: an fMRI study

Table 2 Random effects analysis between groups

Group	P value	K_E	Z	Co-ords	Region
All scenes versus baseline
HO>AD	0.06	38	3.67	−28 -26 -16	Hippocampus/parahippocampal gyrus*
MCI>AD	0.03	73	4.25	−28 -26 -16	Hippocampus/parahippocampal gyrus*
Neutral versus baseline
HO>AD	0.02	119	4.65	−30 -26 -16	Hippocampus/parahippocampal gyrus*
MCI>AD	0.02	106	4.85	−30 -26 -16	Hippocampus/parahippocampal gyrus*
Emotional versus baseline : n/s (but clusters in similar locations to above at lower threshold)
Emotional versus neutral : n/s

IQ and gender entered as covariates into the analysis. Analysis thresholded at p = 0.001 uncorrected.* = small volume correction for MTL applied. K_E = cluster size in voxels.

ISSN: 1471-244X