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Table 3 Absolute numbers (cells/μl) of leukocyte subpopulations and plasma cytokine levels (pg/ml) in PTSD patients versus healthy controls

From: Posttraumatic stress disorder is associated with an enhanced spontaneous production of pro-inflammatory cytokines by peripheral blood mononuclear cells

 

PTSD

Controls

  

Parameter

25% Quantile

Median

75% Quantile

25% Quantile

Median

75% Quantile

F

p

Leukocytes

5350

5820

6940

4927.5

5705

6477.5

.84

.38

Lymphocytes

1795.21

2012.1

2352.59

1611.84

1789.82

2102.555

1.77

.19

Neutrophils

2696.68

3265.82

3865.63

2696.17

2990.00

3798.70

.28

.63

Monocytes

409.74

481.28

541.13

370.13

430.44

536.72

.32

.59

Eosinophils

114.95

168.33

225.83

70.92

100.06

181.63

2.55

.12

Basophils

18.02

22.0

30.1

17.40

21.05

30.08

.09

.77

IL-6

0.2

0.5

0.9

0.07

0.35

0.73

.13

.72

IL-8

3.2

5.2

10.4

5.2

8.6

15.9

4.8

.03#

IL-10

0.08

0.20

0.35

0.06

0.20

1.52

2.7

.08

TNF-α

0.19

0.21

0.24

0.21

0.24

0.44

1.1

.37

MCP-1

1.15

2.00

4.05

0.83

2.30

5.95

.06

.82

  1. * Statistical significance for differences in means of immune parameters was assessed by nonparametric permutation tests, using 10,000 random permutations of residuals under the reduced model.
  2. # Statistical significance was lost after correction for multiple comparisons with Holm’s stepwise procedure.