Plasma brain-derived neurotrophic factor levels, learning capacity and cognition in patients with first episode psychosis

Table 3 Simple linear regression analyses results of the association between cognition and plasma BDNF levels, pharmacological treatment, IQ, negative symptoms or drug use in the first episode patient group at 6 months after first hospitalisation

	Similarities		Digit-symbol coding		Logical memory learning curve		Verbal paired associates I learning curve		Verbal paired associates II
	r ²	ß(P)	r ²	ß(P)	r ²	ß(P)	r ²	ß(P)	r ²	ß(P)
BDNF plasma levels	0.194	0.468	0.130	0.397	0.291	0.559	0.140	0.409	0.118	0.382
BDNF plasma levels	(0.006)		(0.024)		(0.001)		(0.018)		(0.028)
Pharmacological treatment	−0.027	0.025	−0.025	−0.056	0.011	0.193	−0.002	−0.157	0.002	−0.117
Pharmacological treatment	(0.883)		(0.743)		(0.245)		(0.346)		(0.305)
Wechsler Vocabulary (IQ)	0.432	0.669	0.262	0.531	−0.028	−0.015	0.007	0.183	0.224	0.495
Wechsler Vocabulary (IQ)	(0.000)		(0.001)		(0.928)		(0.270)		(0.002)
Negative symptoms (PANSS N)	0.257	−0.530	0.081	−0.335	−0.033	−0.014	0.038	−0.264	0.052	−0.288
Negative symptoms (PANSS N)	(0.002)		(0.066)		(0.939)		(0.145)		(0.110)
Tobacco use	0.034	0.246	0.080	0.325	0.074	0.315	−0.011	0.127	1.046	0.120
Tobacco use	(0.136)		(0.050)		(0.054)		(0.449)		(0.302)
Alcohol use	−0.020	0.111	−0.020	−1.112	0.001	0.179	0.053	0.287	−0.017	0.120
Alcohol use	(0.538)		(0.541)		(0.320)		(0.105)		(0.505)
Cannabis use	−0.021	−0.102	−0.017	−0.121	−0.027	0.067	0.001	0.178	−0.027	0.064
Cannabis use	(0.568)		(0.503)		(0.706)		(0.314)		(0.719)
Other drugs use	0.025	0.083	0.059	−0.299	−0.018	0.117	−0.013	0.137	−0.032	−0.002
	(0.646)		(0.097)		(0.518)		(0.448)		(0.993)

ISSN: 1471-244X