Table 1 Clinical details of the anticonvulsants prescribed
| Â | Valproate (n=67) | Carbamazepine (n=35) | Lamotrigine (n=57) | Topiramate (n=13) |
|---|---|---|---|---|
Average Age years (range) | 39.3 (23.6-50.0) | 39.6 (20.2-50.0) | 39.1 (20.2.-50.0) | 40.7 (28.1-48.5) |
Average duration of treatment months (range) | 27 (1–91) | 49 (1–238) | 32 (1–90) | 14 (1–62) |
ICD 10 Diagnosis | Â | Â | Â | Â |
Bipolar Affective Disorder % (n) | 39 (26) | 37 (13) | 37 (21) | 46 (6) |
Unipolar Depression % (n) | 21 (14) | 43 (15) | 49 (29) | 38 (5) |
Schizoaffective Disorder % (n) | 10 (7) | 0 (0) | 5 (3) | 0 (0) |
Schizophrenia % (n) | 8 (5) | 0 (0) | 2 (2) | 0 (0) |
Emotionally Unstable PD % (n) | 10 (6) | 6 (2) | 0 (0) | 8 (1) |
Cyclothymia % (n) | 8 (5) | 3 (1) | 2 (1) | 0 (0) |
Other % (n) | 6 (4) | 11 (4) | 2 (1) | 8 (1) |
Mean dose of medication/day mg/day (range) | 987 (100–2000) | 455 (200–800) | 166 (25–300) | 192 (45–400) |
Mean Dose/day (DDD)1 | 0.66 | 0.46 | 0.55 | 0.65 |