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Table 1 Studies of guideline concordance in bipolar disorder

From: Pharmacotherapy for bipolar disorder and concordance with treatment guidelines: survey of a general population sample referred to a tertiary care service

 

Population

N

Guidelines

% Concordance

Unutzer et al. 2000 [30]

Out-patients

1246 BD

Expert consensus panel

83%

Lim et al. 2001 [24]

In-patients

1421 BDI

Expert consensus panel

Manic with psychotic features: 38% without: 16%; Depressive with psychotic features: 31%; without: 17%

Simon et al. 2004 [31]

Out-patients

665 BDI + 239 BDII

Several guidelines

BDI: 65.4% BDII: 52.7%

Kilbourne et al. 2005 [32]

In- and out-patients

2316 BDI

APA and Department of Veterans Affairs

Bipolar specific MS: 74.6% Any MS or neuroleptics second generation: 84.4%

Farrelly et al. 2006 [33]

Out-patients

224 mood episodes in 84 BD I and II

British Association for Psychopharmacology

Manic: 81% Depressive: 64% Mixed: 62%

Dennehy et al. 2007 [29]

Out-patients

469 BDI 198 BDII

Several guidelines

Depressive: 83.4% Hypomanic/manic: 81.9% Mixed: 81.8%

Bush et al. 2007 [34]

In- and out-patients

2644 BDI

Several guidelines

67%

Arvilommi et al. 2007 [25]

In- and out-patients

BDI – 90 BDII- 101

Several guidelines

BDI: 55.6% BDII: 30.7%

Smith et al. 2008 [27]

In-patients

23 BD

Expert consensus panel

52% in naturalistic settings, increased to 75% after intervention

Bauer et al. 2009 [28]

 

306 (87% BDI)

Department of Veterans Affairs

50%-60% at index hospitalization in collaborative model; declined to 30%-40% after two years

Altinbas et al. 2011 [26]

Out-patients

263 depressive episodes in 142 patients (131 BDI)

Turkish Psychiatric Association Guidelines for Bipolar Disorder

Severity of the episode: Mild: 29.%; Moderate or severe without psychosis: 27.4%; severe with psychos: 87.5%

  1. BD Bipolar Disorder, BDI Bipolar Disorder type I, BDII Bipolar Disorder type II, MS Mood Stabilizer, APA American Psychiatric Association.