Figure 2

S100B concentration in patients treated with clozapine. S100B concentration plotted against (A) age, (B) time on clozapine treatment in years, (C) BPRS and (D) SANS. No notable correlations between S100B concentration any of these parameters in patient group were observed: age (Pearson’s correlation; r = −0.06026; p value (two tailed) = 0.7653 for control, Pearson’s correlation; r = 0.09035; p value (two tailed) = 0.3763 for clozapine treated patients), treatment time (Pearson’s correlation; r = −0.02633; p value (two tailed) = 0.7980), acute illness severity (BPRS) (Pearson’s correlation; r = 0.04655; p value (two tailed) = 0.649), negative symptoms illness severity (SANS) (Pearson’s correlation; r = 0.1874; p value (two tailed) = 0.8547), where the alpha value = 0.05. White circles (controls), black circles (patients).