Table 2 Clinical risk factors by probable HIV dementia (PHD)
Clinical condition | Number in study (N,%) | Probable HIV dementia (n,%) | Unadjusted OR (95% CI) | Adjusted ORĀ§(95% CI) |
|---|---|---|---|---|
Diagnosis of post traumatic stress disorder | Ā | Ā | P=0.303 | P=0.302 |
Present | 10 (1.6) | 8 (80.0) | 2.27 (0.48-10.8) | 2.28 (0.48-10.91) |
Diagnosis of generalized anxiety disorder | Ā | Ā | P=0.166 | P=0.5730 |
Present | 5 (0.81) | 5 (100) | P=0.559 | P= 0.5309 |
Alcohol dependency disorder | Ā | Ā | P=0.561 | P=0.573 |
Present | 4 (0.65) | 2 (50.0) | 0.56 (0.08-3.99) | 0.56 (0.08-4.11) |
Major depressive disorder | Ā | Ā | P=0.531 | P=0.514 |
Present | 50 (8.1) | 30 (60.0) | 0.83 (0.46-1.49) | 0.82 (0.45-1.49) |
Most Recent CD4 count (cells/Ī¼L) | Ā | Ā | P=0.088 | P=0.061 |
<100 | 66 (12.5) | 52 (78.8) | 1 | 1 |
100-249 | 159 (30.2) | 105 (66.0) | 0.52 (0.27-1.03) | 0.52 (0.26-1.03) |
250-349 | 81 (15.4) | 46 (56.8) | 0.35 (0.17-0.74) | 0.34 (0.16-0.72) |
350+ | 220 (35.6) | 142 (64.6) | 0.49 (0.26-0.94) | 0.47 (0.24-0.91) |
BMI Index | Ā | Ā | P=0.205 | P=0.166 |
Underweight | 56 (9.2) | 32 (57.1) | 1 | 1 |
Normal | 388 (64.9) | 262 (67.5) | 1.56 (0.88-2.76) | 1.58 (0.88-2.81) |
Overweight | 117 (20.0) | 65 (55.6) | 0.94 (0.49-1.78) | 0.93 (0.48-1.80) |
Obese | 35 (5.9) | 20 (57.1) | 1.00 (0.42-2.35) | 0.93 (0.38-2.24) |
ON HAART | Ā | Ā | P=0.559 | P=0.5309 |
Yes | 399 (64.6) | 259 (64.1) | 1.11 (0.79-1.56) | 1.09 (0.76-1.58) |
No | 219 (35.4) | 137 (62.6) | 1 | 1 |