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Table 5 Overall, mild and moderate sample. Changes in the EQ-5D within and between the intervention and usual care group with missing data replaced using last value carried forward

From: Effectiveness of a psycho-educational group program for major depression in primary care: a randomized controlled trial

   

Usual care group (n=112)

  

Intervention group (n=119)

 

Difference (95% CI) between groups (intervention group -usual care group)**

Sample

Months

mean (SD)

Difference*(95% CI)

SRM#

mean (SD)

Difference*(95% CI)

SRM#

Difference

P-value

SES$

 

Pre-intervention

53.25 (17.63)

  

50.76 (18.73)

     
 

3 (Post-intervention)

55.54 (16.36)

2.29 (4.6 to −0.01)

0.19

59.7 (18.1)

8.97(12.20 to 5.72)

0.50

4.19 (−0.31 to 8.66)

0.067

0.26

Overall

6

57.05 (16.97)

3.80 (6.98 to 0.61)

0.22

57.9 (20.7)

7.09 (10.78 to 3.39)

0.34

0.81 (−4.12 to 5.73)

0.748

0.05

 

9

57.69 (17.35)

4.44 (8.0 to 0.87)

0.23

59.2 (20.8)

8.46 (11.99 to 4.93)

0.43

1.54 (−3.43 to 6.51)

0.543

0.09

   

Usual care group (n=48)

  

Intervention group (n=37)

    
 

Pre-intervention

57.92 (18.10)

  

57.81 (17.58)

     

Mild

3 (Post-intervention)

60.71 (16.00)

2.79 (6.17 to −0.59)

0.24

65.7 (16.7)

7.89(13.84 to 1.94)

0.44

4.99 (−2.11 to 12.09)

0.166

0.31

 

6

60.90 (16.49)

2.98 (7.71 to −1.75)

0.18

64 (18.1)

6.14 (12.73 to −0.47)

0.31

3.05 (−4.43 to 10.53)

0.420

0.18

 

9

62.52 (15.02)

4.60(9.75 to −0.54)

0.25

67.8 (20.5)

9.97 (16.82 to 3.11)

0.48

5.26 (−2.39 to 12.92)

0.175

0.35

   

Usual care group (n=64)

  

Intervention group (n=82)

    
 

Pre-intervention

49.75 (16.56)

  

47.59 (18.46)

     
 

3 (Post-intervention)

51.67 (15.67)

1.92 (5.15 to −1.31)

0.15

57.04 (18.08)

9.45(13.39 to 5.50)

0.52

5.36 (−0.263 to 10.99)

0.062

0.34

Moderate

6

54.17 (16.88)

4.42 (8.82 to 0.02)

0.25

55.11 (21.35)

7.52 (12.07 to 2.97)

0.36

0.93 (−5.49 to 7.37)

0.774

0.06

 

9

54.06 (18.20)

4.31 (89.33 to −0.70)

0.21

55.37 (19.83)

7.78 (11.95 to 3.60)

0.40

1.30 (−5.00 to 7.61)

0.684

0.07

  1. Abbreviations: SD standard deviation. CI confidence interval.
  2. * Differences were calculated between follow-up measurement and baseline measurement.
  3. Positive differences indicate improvement; a negative one denotes some worsening on clinical measures.
  4. # SRM: Standardized response mean. Calculated as the mean change in score divided by the standard deviation of the change in score.
  5. $ SES: Standardized effect size was computed as the mean difference between intervention and control group divided by the standard deviation of the control measurement.
  6. A positive SRM denotes improvement; a negative one denotes some worsening on clinical measures.
  7. ** Difference was calculated between intervention group and control group.
  8. Positive differences indicate improvement in the intervention group. Negative differences denote worsening in the intervention group.
  9. Interpretation effect sizes: Values 0.2-0.5 represent small changes, 0.5-0.8 moderate changes and >0.8 large changes.