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Table 2 Baseline characteristics for all patients and for patients remained vs. patients who discontinued within 6 months from baseline

From: Schizophrenia symptoms and functioning in patients receiving long-term treatment with olanzapine long-acting injection formulation: a pooled analysis

  Patients n (%)  
Characteristic (%) Remained (N = 843) Discontinued (N = 339) Total (N = 1182) p-value
Geographic Region     0.129
 Western Europe 148 (68.8) 67 (31.2) 215  
 Eastern Europe 237 (75.2) 78 (24.8) 315  
 Americas 380 (69.1) 170 (30.9) 550  
 Other 78 (76.5) 24 (23.5) 102  
Gender     0.391
 Female 274 (69.7) 119 (30.3) 393  
 Male 569 (72.1) 220 (27.9) 789  
EPS     0.180
 No 542 (74.0) 190 (26.0) 732  
 Yes 113 (68.9) 51 (31.1) 164  
Working Status     0.003
 Unemployed disab. 349 (70.2) 148 (29.8) 497  
 Paid work 181 (81.2) 42 (18.8) 223  
 Retired 101 (82.1) 22 (17.9) 123  
 Keeping house 73 (70.2) 31 (29.8) 104  
 Unemployed unrel. 61 (81.3) 14 (18.7) 75  
 Student 33 (89.2) 4 (10.8) 37  
 Volunteer 23 (69.7) 10 (30.3) 33  
 Self-employed 15 (78.9) 4 ( 21.1) 19  
Baseline Remission     
 Cross-sectional 455 (74.6) 155 (25.4) 610 0.010
Mean (SD)     
Age [year] 39.4 (11.43) 40.1 (10.89) 39.6 (11.28) 0.293
PANSS Total 61.4 (16.20) 64.1 (16.66) 62.1 (16.37) 0.012
PANSS POS 2.1 (0.66) 2.3 (0.77) 2.1 (0.70) <0.001
PANSS NEG 2.4 (0.83) 2.4 (0.83) 2.4 (0.83) 0.969
PANSS DIS 2.1 (0.66) 2.2 (0.68) 2.1 (0.67) 0.274
PANSS HOS 1.5 (0.62) 1.7 (0.70) 1.6 (0.65) 0.003
PANSS DEP 1.9 (0.70) 2.0 (0.71) 1.9 (0.70) 0.015
QLS Total 1.8 (1.84) 1.4 (1.73) 1.7 (1.81) 0.001
QLS Interpersonal relations 2.8 (1.19) 2.7 (1.19) 2.8 (1.19) 0.074
QLS Instrumental role funct 2.5 (1.49) 2.2 (1.45) 2.4 (1.49) <0.001
CGI-S 3.0 (0.93) 3.3 (0.97) 3.1 (0.95) <0.001
No. of previous episodes 1.4 (1.53) 1.8 (2.74) 1.5 (1.91) 0.121
  1. CGI-S: Clinical Global Impression – Severity, EPS: extrapyramidal symptoms, PANSS: Positive and Negative Symptoms Score, QLS: Heinrich Carpenter’s Quality of Life Scale, SD: standard deviation.