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Table 2 Baseline characteristics for all patients and for patients remained vs. patients who discontinued within 6 months from baseline

From: Schizophrenia symptoms and functioning in patients receiving long-term treatment with olanzapine long-acting injection formulation: a pooled analysis

 

Patients n (%)

 

Characteristic (%)

Remained (N = 843)

Discontinued (N = 339)

Total (N = 1182)

p-value

Geographic Region

   

0.129

 Western Europe

148 (68.8)

67 (31.2)

215

 

 Eastern Europe

237 (75.2)

78 (24.8)

315

 

 Americas

380 (69.1)

170 (30.9)

550

 

 Other

78 (76.5)

24 (23.5)

102

 

Gender

   

0.391

 Female

274 (69.7)

119 (30.3)

393

 

 Male

569 (72.1)

220 (27.9)

789

 

EPS

   

0.180

 No

542 (74.0)

190 (26.0)

732

 

 Yes

113 (68.9)

51 (31.1)

164

 

Working Status

   

0.003

 Unemployed disab.

349 (70.2)

148 (29.8)

497

 

 Paid work

181 (81.2)

42 (18.8)

223

 

 Retired

101 (82.1)

22 (17.9)

123

 

 Keeping house

73 (70.2)

31 (29.8)

104

 

 Unemployed unrel.

61 (81.3)

14 (18.7)

75

 

 Student

33 (89.2)

4 (10.8)

37

 

 Volunteer

23 (69.7)

10 (30.3)

33

 

 Self-employed

15 (78.9)

4 ( 21.1)

19

 

Baseline Remission

    

 Cross-sectional

455 (74.6)

155 (25.4)

610

0.010

Mean (SD)

    

Age [year]

39.4 (11.43)

40.1 (10.89)

39.6 (11.28)

0.293

PANSS Total

61.4 (16.20)

64.1 (16.66)

62.1 (16.37)

0.012

PANSS POS

2.1 (0.66)

2.3 (0.77)

2.1 (0.70)

<0.001

PANSS NEG

2.4 (0.83)

2.4 (0.83)

2.4 (0.83)

0.969

PANSS DIS

2.1 (0.66)

2.2 (0.68)

2.1 (0.67)

0.274

PANSS HOS

1.5 (0.62)

1.7 (0.70)

1.6 (0.65)

0.003

PANSS DEP

1.9 (0.70)

2.0 (0.71)

1.9 (0.70)

0.015

QLS Total

1.8 (1.84)

1.4 (1.73)

1.7 (1.81)

0.001

QLS Interpersonal relations

2.8 (1.19)

2.7 (1.19)

2.8 (1.19)

0.074

QLS Instrumental role funct

2.5 (1.49)

2.2 (1.45)

2.4 (1.49)

<0.001

CGI-S

3.0 (0.93)

3.3 (0.97)

3.1 (0.95)

<0.001

No. of previous episodes

1.4 (1.53)

1.8 (2.74)

1.5 (1.91)

0.121

  1. CGI-S: Clinical Global Impression – Severity, EPS: extrapyramidal symptoms, PANSS: Positive and Negative Symptoms Score, QLS: Heinrich Carpenter’s Quality of Life Scale, SD: standard deviation.