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Table 4 Underactive regions during self-evaluation (vs. other-evaluation) in patients (vs. controls): group x level interaction (Figures 2 and 3)

From: Self-evaluation in schizophrenia: an fMRI study with implications for the understanding of insight

Cerebral region

Peak talairach coordinates x, y, z(range)

3-D Cluster size (in voxels)

Significance level

COMBINED TRAITS

   

Left Superior Frontal Gyrus, BA9

-6, 53, 32(x: -6 – 19, y: 37-53, z: 27-42 includes BA8)

31

p = 0.0006

Right Superior (& Medial) Frontal Gyrus, BA9

   
  

26

 

Right Posterior Cingulate, BA23*

-1, -55, 16(x: -3 – 7, y: -51-56, z: 16-26 includes L post. cingulate)

26

p = 0.0053

POSITIVE TRAITS

   

Right Medial Frontal Gyrus, BA9

4, 48, 26

39

p = 0.0012

NEGATIVE TRAITS

   

Left Superior Frontal Gyrus, BA9

-4, 48, 31

42

p = 0.0016

MENTAL ILLNESS TRAITS

   

Right Inferior Parietal Lobule, BA40

47, -33, 37

13

p = 0.0059#

PHYSICAL ILLNESS TRAITS

   

Right Middle Occipital Gyrus, BA18/19

33, 82, 8

56

p = 0.0007

  1. *Became significant after analysis with response time as a co-variate.
  2. #Cluster level significance level, p<.005. BA: Brodmann Area.