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Table 1 Baseline and pre-index characteristics of propensity score-matched study sample

From: One-year risk of psychiatric hospitalization and associated treatment costs in bipolar disorder treated with atypical antipsychotics: a retrospective claims database analysis

Variable

Aripiprazole (n = 461)

Ziprasidone (n = 461)

p-value

Aripiprazole (n = 737)

Olanzapine (n = 737)

p-value

Aripiprazole (n = 770)

Quetiapine (n = 770)

p-value

Aripiprazole (n = 771)

Risperidone (n = 771)

p-value

Age, mean (SD)

37.4 (11.6)

37.9 (11.1)

0.514

37.5 (12.0)

37.7 (11.9)

0.758

37.1 (11.9)

36.5 (11.4)

0.315

37.1 (11.9)

37.1 (11.2)

0.998

Sex, n (% men)

337 (73.1)

333 (722)

0.995

483 (65.5)

467 (63.4)

0.384

515 (66.9)

541 (70.3)

0.154

515 (66.8)

511 (66.3)

0.829

Psychiatric hospitalization, n (%)

159 (34.5)

160 (34.7)

0.945

179 (24.3)

182 (24.7)

0.856

178 (23.1)

178 (23.1)

1.000

180 (23.3)

180 (23.3)

1.000

Diabetes, n (%)

36 (7.8)

33 (7.2)

0.707

40 (5.4)

47 (6.4)

0.439

45 (5.8)

38 (4.9)

0.430

45 (5.8)

44 (5.7)

0.913

Hyperlipidemia, n (%)

75 (16.3)

81 (17.6)

0.598

123 (16.7)

131 (17.8)

0.581

130 (16.9)

130 (16.9)

1.000

130 (16.9)

119 (15.4)

0.446

Mood stabilizer exposure, n (%):

            

   Carbamazapine

13 (2.8)

15 (3.3)

0.701

25 (3.4)

27 (3.7)

0.778

28 (3.6)

29 (3.8)

0.893

27 (3.5)

29 (3.8)

0.893

   Lamotrigine

72 (15.6)

75 (16.3)

0.787

116 (15.7)

115 (15.6)

0.943

137 (17.8)

134 (17.4)

0.841

136 (17.6)

134 (17.4)

0.841

   Lithium

67 (14.5)

70 (15.2)

0.781

106 (14.4)

104 (14.1)

0.882

115 (14.9)

108 (14.0)

0.612

115 (14.9)

108 (14.0)

0.612

   Oxcarbazepine

34 (7.4)

38 (8.2)

0.623

60 (8.1)

65 (8.8)

0.640

75 (9.7)

68 (8.8)

0.539

75 (9.7)

68 (8.8)

0.539

   Topiramate

43 (9.3)

46 (10.0)

0.738

68 (9.2)

65 (8.8)

0.785

81 (10.5)

85 (11.0)

0.742

80 (10.4)

85 (11.0)

0.742

   Valproate

83 (18.0)

84 (18.2)

0.932

159 (21.6)

156 (21.2)

0.849

165 (21.4)

168 (21.8)

0.853

165 (21.4)

168 (21.8)

0.853

Charlson comorbidity index, mean (SD)

0.3 (0.7)

0.4 (0.9)

0.388

0.3 (0.7)

0.3 (0.8)

0.432

0.2 (0.6)

0.2 (0.7)

0.746

0.3 (0.8)

0.3 (0.8)

0.468

  1. P-values were calculated based on t-tests for continuous variables and chi square tests for categorical variables.