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Figure 4 | BMC Psychiatry

Figure 4

From: Dose-associated changes in safety and efficacy parameters observed in a 24-week maintenance trial of olanzapine long-acting injection in patients with schizophrenia

Figure 4

Regression scatterplot of mean change in PANSS total score (LOCF) by dose. Figure 4 shows the scatterplot, regression line, and resulting equation for the relationship between endpoint PANSS total score change and dose (R2 = 0.0133). In the equation, "dose" refers to the calculated oral equivalent daily dose (10.7, 14.5, or 21.4 mg/day), not the actual injected dose. Abbreviations: OLZ LAI = olanzapine long-acting injection; OLZ LAI 150 = group receiving low-dose olanzapine LAI, 150 mg every 2 weeks, approximate oral equivalent 10 mg/day (N = 140); OLZ LAI 405 = group receiving medium-dose olanzapine LAI, 405 mg every 4 weeks, approximate oral equivalent 15 mg/day (N = 318); and OLZ LAI 300 = group receiving high-dose olanzapine LAI, 300 mg every 2 weeks, approximate oral equivalent 20 mg/day (N = 141).

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