Skip to main content
Figure 3 | BMC Psychiatry

Figure 3

From: Dose-associated changes in safety and efficacy parameters observed in a 24-week maintenance trial of olanzapine long-acting injection in patients with schizophrenia

Figure 3

Kaplan-Meier survival analysis of time to relapse by dose group. Figure 3 illustrates the survival curves for time to relapse by dose group. Relapse or "psychotic exacerbation" was defined as 1) an increase of any BPRS positive symptom item to a score >4, with an absolute increase ≥2 for the specific item since randomization, 2) an increase of any BPRS positive symptom item to a score >4, with an absolute increase ≥4 on the positive symptom subscale since randomization; or 3) hospitalization as the result of worsening of positive psychotic symptoms. Median time to relapse not reported because no group had >50% rate of relapse. Abbreviations: OLZ LAI = olanzapine long-acting injection; OLZ LAI 150 = group receiving low-dose olanzapine LAI, 150 mg every 2 weeks, approximate oral equivalent 10 mg/day (N = 140); OLZ LAI 405 = group receiving medium-dose olanzapine LAI, 405 mg every 4 weeks, approximate oral equivalent 15 mg/day (N = 318); and OLZ LAI 300 = group receiving high-dose olanzapine LAI, 300 mg every 2 weeks, approximate oral equivalent 20 mg/day (N = 141).

Back to article page