From: Treatment patterns associated with Duloxetine and Venlafaxine use for Major Depressive Disorder
Previous Medication Use | Duloxetine Group, % (n = 9,641) | Venlafaxine XR Group, % (n = 8,514) | p-value |
---|---|---|---|
Antidepressants | |||
SSRIs | 59.5 | 52.7 | .0001 |
TCAs | 12.6 | 7.8 | .0001 |
MAOIs | 0.2 | 0.1 (NS) | .275 |
Other antidepressants | 45.0 | 36.5 | .0001 |
Anxiolytics | 57.0 | 47.4 | .0001 |
Benzodiazepines | 53.8 | 44.5 | .0001 |
Buspirone | 4.8 | 4.1 (NS) | .015 |
Hydroxyzine | 5.7 | 4.9 (NS) | .009 |
Anticonvulsants | 30.1 | 17.9 | .0001 |
Antipsychotics | 20.0 | 15.4 | .0001 |
Atypical | 17.8 | 13.2 | .0001 |
Typical | 3.5 | 2.9 (NS) | .021 |
Analgesics | 63.1 | 51.3 | .0001 |
Skeletal-muscle relaxants | 26.5 | 17.1 | .0001 |
Antimigraine medications | 12.3 | 9.2 | .0001 |
Hypnotics | 30.2 | 22.3 | .0001 |
Other medications | |||
Antiulcer drugs | 29.4 | 22.7 | .0001 |
Antihyperlipidemics | 20.0 | 15.5 | .0001 |
Antihypertensives | 17.9 | 13.9 | .0001 |
Antiasthmatics | 17.7 | 15.4 | .0001 |
ADHD medications | |||
Stimulants | 13.6 | 9.2 | .0001 |
Atomoxetine | 2.0 | 1.7 (NS) | .079 |
Antihistamines | 10.3 | 6.7 | .0001 |
β-Adrenoceptor blockers | 8.9 | 7.3 | .0001 |
Antidiabetics | 9.0 | 6.7 | .0001 |
Antimanics | 3.0 | 2.3 | .001 |
≥3 unique antidepressants | 20.8 | 16.6 | .0001 |
≥3 unique pain medications | 25.5 | 15.6 | .0001 |