Restraint of appetite and reduced regional brain volumes in anorexia nervosa: a voxel-based morphometric study

BMC Psychiatry

Table 2 Whole brain tissue volume data in women with anorexia nervosa, restricting anorexia nervosa, binge-purge anorexia nervosa and healthy controls

Tissue	AN (n = 14) Mean ± SEM	HC (n = 21) Mean ± SEM	AN vs. HC t-value	AN vs. HC p-value	RAN (n = 8) Mean ± SEM	BPAN (n = 6) Mean ± SEM	RAN v. BPAN t-value	RAN vs. BPAN p-value
Gray Matter Volume, cm³	88.16 ± 2.55	91.80 ± 2.19	1.074	ns	87.30 ± 3.09	89.29 ± 4.58	0.374	ns
White Matter Volume, cm³	54.09 ± 1.13	52.25 ± 1.21	1.059	ns	54.43 ± 1.88	53.65 ± 1.05	0.331	ns
CSF Volume, cm³	142.25 ± 3.28	144.05 ± 2.71	0.422	ns	141.74 ± 0.44	142.94 ± 5.35	0.175	ns

AN = Anorexia Nervosa, HC = Healthy Control, RAN = Restricting Anorexia Nervosa, BPAN = Binge-Purge Anorexia Nervosa, SEM = Standard Error Mean, CSF = Cerebro-Spinal Fluid, ns = non significant

ISSN: 1471-244X