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Table 1 Clinical characteristics of subjects

From: Restraint of appetite and reduced regional brain volumes in anorexia nervosa: a voxel-based morphometric study

Variable

AN (n = 14)

Mean Ā± SEM

HC (n = 21)

Mean Ā± SEM

AN v. HC

t-value

AN v. HC

p-value

RAN (n = 8)

Mean Ā± SEM

BPAN (n = 6)

Mean Ā± SEM

RAN v. BPAN

t-value

RAN v. BPAN

p-value

Age, years

26 Ā± 1.9

26 Ā± 2.1

0.16

ns

26 Ā± 2.9

27 Ā± 2.6

0.9

ns

BMI at scan, kg/m 2

15.6 Ā± 0.4

21.4 Ā± 0.5

8.4

<0.01

15.1 Ā± 0.5

16.2 Ā± 0.3

1.7

ns

Lowest lifetime BMI, kg/m 2

12.4 Ā± 0.3

19.6 Ā± 0.3

10.6

<0.01

11.7 Ā± 0.4

13.4 Ā± 0.4

2.9

0.01

Education (from 11 yrs old), years

7.2 Ā± 0.6

11.5 Ā± 1.4

2.4

0.02

6.8 Ā± 0.6

7.8 Ā± 1.0

0.9

ns

Duration Illness, years

9.2 Ā± 1.9

--

--

--

9.2 Ā± 3.1

9.2 Ā± 2.2

0

ns

EDE-Q (0-6), restrained eating

3.0 Ā± 0.5

1 Ā± 0.2

4.9

<0.01

2 Ā± 0.5

4 Ā± 0.7

1.8

ns

EDE-Q (Q8) No. of binges month (0-6)*

1 Ā± 0.5

--

--

--

--

4 Ā± 0.8

--

--

EDE-Q (Q22), No. of vomits in month

5.8 Ā± 1.6

--

--

--

--

8 Ā± 2.5

--

--

HADS- Anxiety (0-21)

13.9 Ā± 0.8

4.4 Ā± 0.6

9.5

<0.01

13 Ā± 1.2

15.2 Ā± 1.0

1.3

ns

HADS- Depression (0-21)

10.3 Ā± 1.2

1.6 Ā± 0.4

7.8

<0.01

8.8 Ā± 1.8

12.3 Ā± 1.5

1.5

ns

  1. AN = Anorexia Nervosa, HC = Healthy Control, RAN = Restricting Anorexia Nervosa, BPAN = Binge Purge Anorexia Nervosa, SEM = Standard Error Mean, BMI = Body Mass Index, EDE-Q = Eating Disorder Examination Questionnaire, HADS = Hospital Anxiety and Depression Scale, ns = non significant, *an average score of 1 on the EDE-Q, Question 8, represents binges on 1-5 days per month, whereas an average score of 4 represent binges on 16-22 days per month