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Table 1 Overview of assessments and instruments

From: Cocaine Addiction Treatments to improve Control and reduce Harm (CATCH): New Pharmacological Treatment Options for Crack-Cocaine Dependence in the Netherlands

Assessments (researchers) Baseline Week 4 Week 8 Week 12
Checklist inclusion criteria (control and experimental)    
CIDI - Substance Abuse Module (cocaine& heroine& alcohol)    
MINI - Suicidal risk    
Addiction Severity Index + supplement1    
Addiction Severity Index; short version substance use + supplement1  
Time Line Follow-Back (cocaine)
Maudsley Addiction Profile (MAP) - HSS
Symptom Check List- 90 (SCL-90)
Obsessive Compulsive Drug Use Scale (OCDUS)
Client Satisfaction Questionnaire- 8 (CSQ-8) + supplement2    
Evaluation (control and experimental)    
Medical assessment (physician) Baseline Week 4 Week 8 Week 12
Checklist exclusion criteria (control and experimental)    
First informed consent (control and experimental)    
Second informed consent (only experimental)    
Medical assessment: ECG (only dexamphetamine study)   
Medical assessment: blood analysis (week 12 only experimental)   
Medical screening: heart rate, blood pressure3 (only experimental) • • • • • • • • • • • •
Pregnancy (only experimental; only women)
(Serious) adverse events (only experimental) • • • • • • • • • • • •
Drug accountability (only dexamphetamine study)   • • • • • • • • • • • •
Urinalysis cocaine- metabolites (control and experimental; obtained by research assistant)    • • • •
Treatment participation (consumption of care; medication) (control and experimental)   • • • • • • • • • • • •
  1. Note. The assessments in week 4 and 8 are only for participants in the experimental groups (topiramate, modafinil, dexamphetamine SR), 1 The ASI-supplement concerns illegal activities, income, and living arrangements, 2 Additional questions about the treatment(s), 3 In the dexamphetamine study, blood pressure and heart rate will be assessed every day during the first four weeks, • • • • Indicates weekly (instead of monthly) registration.