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Table 5 QTDT analysis.

From: Genetic influences on attention deficit hyperactivity disorder symptoms from age 2 to 3: A quantitative and molecular genetic investigation

  

ADHD Composite Age 2

ADHD Composite Age 3

Gene

Marker

AT

AW

AT

AW

  

χ 2

df

P

χ 2

df

P

χ 2

df

p

χ 2

df

p

DRD4

Exon 3 VNTR

4.74

3

0.19

3.26

3

0.35

7.82

3

0.05

8.69

3

0.03

DAT1

3'UTR VNTR

7.00

2

0.03

5.09

2

0.08

11.15

2

0.004

12.17

2

0.002*

 

Int8 VNTR

3.42

2

0.18

2.84

2

0.24

2.90

2

0.24

3.21

2

0.20

 

rs11564750

0.06

1

0.80

0.75

1

0.39

0.14

1

0.43

0.01

1

0.94

 

rs2550946

0.43

1

0.51

0.71

1

0.40

0.16

1

0.47

0.99

1

0.32

SNAP25

rs6039806

0.00

1

0.96

0.00

1

0.99

0.08

1

0.97

0.41

1

0.52

 

rs362987

0.04

1

0.84

0.07

1

0.79

0.04

1

0.91

0.39

1

0.39

 

rs3746544

0.05

1

0.83

0.18

1

0.67

1.75

1

0.21

1.98

1

0.16

 

rs1051312

0.63

1

0.43

0.04

1

0.85

0.00

1

0.58

0.65

1

0.42

5-HTT

rs11080121

2.16

1

0.14

2.71

1

0.10

0.12

1

0.23

4.77

1

0.03

 

rs140701

2.96

1

0.09

3.03

1

0.08

0.00

1

0.38

3.24

1

0.07

 

rs2020936

1.24

1

0.27

1.92

1

0.17

1.34

1

0.40

1.20

1

0.27

 

rs2066713

0.04

1

0.84

0.00

11

1.00

1.27

1

0.50

0.32

1

0.57

 

5-HTTLPR

0.31

1

0.57

0.03

1

0.87

0.03

1

0.87

0.91

1

0.34

MAOA

rs6323

NT

NT

NT

1.03

1

0.31

NT

NT

NT

0.97

1

0.83

 

Promoter VNTR

NT

NT

NT

4.68

3

0.20

NT

NT

NT

0.05

3

0.81

NET1

rs11568324

4.38

1

0.04

NT

NT

NT

0.58

1

0.13

NT

NT

NT

 

rs3785157

3.68

1

0.06

4.65

1

0.03

0.37

1

0.48

4.30

1

0.04

 

rs998424

3.30

1

0.07

4.42

1

0.04

0.83

1

0.59

3.22

1

0.07

 

rs2242447

1.23

1

0.27

1.03

1

0.31

3.56

1

0.18

2.01

1

0.16

  1. Nominal p-values < 0.05 are in bold, italicized numbers and those approaching this significance threshold are shown in italics. AT = Total Test of Association, AW = Within-Test of Association. NT = Not tested. X-linked markers tested using UNPHASED. df = difference in degrees of freedom between the null and alternative models. *Significant after bonferroni correction